Technical bulletin



ACTYBIO CMK40 is a preservative with a broad spectrum of action, formulated for the preservation of concrete additives, machining fluids, textile and leather auxiliaries, thickeners, adhesives (including protein-based formulations) and glues, aqueous coatings and in the formulation of disinfectants.


Preservative based on 4-chloro-3-methylphenol (PCMC / CMK).

Mechanism of action:

PCMC / CMK alters the structure of the microorganism’s cell wall, which causes the loss of cell integrity. With this, the biocide molecule accesses and disrupts the membrane cytoplasmic, causing leakage of essential components of the cell, leading to its disintegration.


ACTYBIO CMK40 is a solution of p-chloro-m-cresol (PCMC/CMK). This active ingredient has a broad and balanced spectrum of activity encompassing gram-positive and gram-negative bacteria, mould and yeast fungi.

It is particularly effective against putrefactive bacteria and therefore suitable for use in products that are difficult to preserve (e.g. protein-based formulations).

ACTYBIO CMK40 is partially miscible with water, due to its carrier. The excellent thermal and chemical stability of ATC BIOCIDE CMK40 indicates that it can be incorporated into materials that require preservation at different stages of the production process.